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phenobarbital will lessen the level or effect of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers may lower partiaprevir and ritonavir stages, and so reduced efficacy of Viekira Pakfentanyl intranasal and phenobarbital both of those enhance sedation